I'm a scientific advisor for Kernel, and I think Bryan Johnson is one of the most future-leaning guys I know.
Can we reproduce our brains on other media (say, on computers, or out of beer cans and tennis balls)?
David's iPad app "Why the Net Matters, or Six Ways to Avert the Collapse of Civilization" was recently called a "superbook" by the New York Times Magazine. For a taste of the argument, read David's article in WIRED or watch a video of his talk at the Long Now Foundation. Don't have an iPad? The manuscript is now available as an eBook.
Want to know more about the inner workings of a neuroscience lab? Watch a video profile of David and his students on NOVA Science Now.
Why should the US invest in brain science? See David's opinion in the New York Times.